Inhibition of endothelial cell proliferation and tumor angiogenesis by up-regulating NDRG2 expression in breast cancer cells.

The N-myc downstream-regulated gene 2 (NDRG2) is involved in tumor cell differentiation and apoptosis, but its function in tumor angiogenesis remains to be established. Here, we employed adenovirus overexpressing NDRG2 (Ad-NDRG2) to efficiently up-regulate target gene expression in the NDRG2-low-exp...

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Main Authors: Ji Ma, Wenchao Liu, Xiaohong Yan, Qianrong Wang, Qingli Zhao, Yan Xue, Hui Ren, Lin Wu, Yuanxiong Cheng, Sen Li, Lu Miao, Libo Yao, Jian Zhang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3290656?pdf=render
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