IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

BACKGROUND: High-grade osteosarcoma is an aggressive tumor most often developing in the long bones of adolescents, with a second peak in the 5th decade of life. Better knowledge on cellular signaling in this tumor may identify new possibilities for targeted treatment. METHODS: We performed gene set...

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Autors principals: Kuijjer, Marieke L, Peterse, Elisabeth FP, van den Akker, Brendy EWM, Briaire-de Bruijn, Inge H, Serra, Massimo, Meza-Zepeda, Leonardo A, Myklebost, Ola, Hassan, A Bassim, Hogendoorn, Pancras CW, Cleton-Jansen, Anne-Marie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672007/
https://ncbi.nlm.nih.gov/pubmed/23688189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-245
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