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Candidate Gene Studies of a Promising Intermediate Phenotype: Failure to Replicate

Many candidate gene studies use ‘intermediate phenotypes' instead of disease diagnoses. It has been proposed that intermediate phenotypes have simpler genetic architectures such that individual alleles account for a larger percentage of trait variance. This implies that smaller samples can be u...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hart, Amy B, de Wit, Harriet, Palmer, Abraham A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671998/
https://ncbi.nlm.nih.gov/pubmed/23303064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.245
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