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Candidate Gene Studies of a Promising Intermediate Phenotype: Failure to Replicate
Many candidate gene studies use ‘intermediate phenotypes' instead of disease diagnoses. It has been proposed that intermediate phenotypes have simpler genetic architectures such that individual alleles account for a larger percentage of trait variance. This implies that smaller samples can be u...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671998/ https://ncbi.nlm.nih.gov/pubmed/23303064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.245 |
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