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Candidate Gene Studies of a Promising Intermediate Phenotype: Failure to Replicate
Many candidate gene studies use ‘intermediate phenotypes' instead of disease diagnoses. It has been proposed that intermediate phenotypes have simpler genetic architectures such that individual alleles account for a larger percentage of trait variance. This implies that smaller samples can be u...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671998/ https://ncbi.nlm.nih.gov/pubmed/23303064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.245 |
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