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The structure of allelic diversity in the presence of purifying selection

In the absence of selection, the structure of equilibrium allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical patterns of molecular variation. Along with coalescent theory, it provides statistical techniques for rejecti...

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Detalhes bibliográficos
Main Authors: Desai, Michael M., Nicolaisen, Lauren E., Walczak, Aleksandra M., Plotkin, Joshua B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671953/
https://ncbi.nlm.nih.gov/pubmed/22198521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2011.12.002
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