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The Structure of Genealogies in the Presence of Purifying Selection: A Fitness-Class Coalescent

Compared to a neutral model, purifying selection distorts the structure of genealogies and hence alters the patterns of sampled genetic variation. Although these distortions may be common in nature, our understanding of how we expect purifying selection to affect patterns of molecular variation rema...

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Detalhes bibliográficos
Main Authors: Walczak, Aleksandra M., Nicolaisen, Lauren E., Plotkin, Joshua B., Desai, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276618/
https://ncbi.nlm.nih.gov/pubmed/22135349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.134544
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