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The structure of allelic diversity in the presence of purifying selection

In the absence of selection, the structure of equilibrium allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical patterns of molecular variation. Along with coalescent theory, it provides statistical techniques for rejecti...

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Autors principals: Desai, Michael M., Nicolaisen, Lauren E., Walczak, Aleksandra M., Plotkin, Joshua B.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671953/
https://ncbi.nlm.nih.gov/pubmed/22198521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2011.12.002
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