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The structure of allelic diversity in the presence of purifying selection

In the absence of selection, the structure of equilibrium allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped shape our expectations of empirical patterns of molecular variation. Along with coalescent theory, it provides statistical techniques for rejecti...

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書誌詳細
主要な著者: Desai, Michael M., Nicolaisen, Lauren E., Walczak, Aleksandra M., Plotkin, Joshua B.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671953/
https://ncbi.nlm.nih.gov/pubmed/22198521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2011.12.002
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