Načítá se...
Diverse Effects of Individual Mismatch Repair Components on Transcription-Induced CAG Repeat Instability in Human Cells
Several neurodegerative diseases are caused by expansion of a trinucleotide repeat tract in a critical gene. The mechanism of repeat instability is not yet defined, but in mice it requires MutSβ, a complex of MSH2 and MSH3. We showed previously that transcription through a CAG repeat tract induces r...
Uloženo v:
| Hlavní autoři: | , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671857/ https://ncbi.nlm.nih.gov/pubmed/19497791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.04.024 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|