Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase.

The 5' control region and first exon for human X-chromosome-linked phosphoglycerate kinase is contained in a G + C-rich island. We measured methylation at all HpaII sites in this 5' region of leukocyte DNA. By use of a blotting procedure that allows analysis of small DNA fragments, we found that the...

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Publicado en:	Mol Cell Biol
Autores principales:	Keith, D H, Singer-Sam, J, Riggs, A D
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367182/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025634/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.11.4122-4125.1986
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