Never Cared for What They Do: High Structural Stability of Guanine-Quadruplexes in the Presence of Strand-Break Damage

DNA integrity is an important factor that assures genome stability and, more generally, the viability of cells and organisms. In the presence of DNA damage, the normal cell cycle is perturbed when cells activate their repair processes. Although efficient, the repair system is not always able to ensu...

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Главные авторы:	Tom Miclot, Cécilia Hognon, Emmanuelle Bignon, Alessio Terenzi, Stéphanie Grandemange, Giampaolo Barone, Antonio Monari
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-05-01
Серии:	Molecules
Предметы:	guanine quadruplexes DNA strand breaks molecular modeling and simulation
Online-ссылка:	https://www.mdpi.com/1420-3049/27/10/3256
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