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Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase.

The 5' control region and first exon for human X-chromosome-linked phosphoglycerate kinase is contained in a G + C-rich island. We measured methylation at all HpaII sites in this 5' region of leukocyte DNA. By use of a blotting procedure that allows analysis of small DNA fragments, we foun...

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Hlavní autoři: Keith, D H, Singer-Sam, J, Riggs, A D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC367182/
https://ncbi.nlm.nih.gov/pubmed/3025634
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