Hypercholesterolemia Abrogates Late Preconditioning via a Tetrahydrobiopterin-Dependent Mechanism in Conscious Rabbits

BACKGROUND: Although the late phase of ischemic preconditioning (PC) is known to confer cardioprotection in healthy animal models, it is unknown whether this phenomenon exists in the presence of hypercholesterolemia. The goal of this study was to determine whether the infarct-sparing effect of late...

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Bibliographische Detailangaben
Hauptverfasser: Tang, Xian-Liang, Takano, Hitoshi, Xuan, Yu-Ting, Sato, Hiroshi, Kodani, Eitaro, Dawn, Buddhadeb, Zhu, Yanqing, Shirk, Gregg, Wu, Wen-Jian, Bolli, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671759/
https://ncbi.nlm.nih.gov/pubmed/16186416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.566190
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