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Hypercholesterolemia Abrogates Late Preconditioning via a Tetrahydrobiopterin-Dependent Mechanism in Conscious Rabbits

BACKGROUND: Although the late phase of ischemic preconditioning (PC) is known to confer cardioprotection in healthy animal models, it is unknown whether this phenomenon exists in the presence of hypercholesterolemia. The goal of this study was to determine whether the infarct-sparing effect of late...

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Detalhes bibliográficos
Main Authors: Tang, Xian-Liang, Takano, Hitoshi, Xuan, Yu-Ting, Sato, Hiroshi, Kodani, Eitaro, Dawn, Buddhadeb, Zhu, Yanqing, Shirk, Gregg, Wu, Wen-Jian, Bolli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671759/
https://ncbi.nlm.nih.gov/pubmed/16186416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.566190
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