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Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond
Traditional antidepressants require many weeks to reveal their therapeutic effects. However, the widely replicated observation that a single subanesthetic dose of the NMDA glutamate receptor antagonist, ketamine, produced meaningful clinical improvement within hours suggested that rapidly acting ant...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671489/ https://ncbi.nlm.nih.gov/pubmed/23726151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.03.026 |
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