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Double stable isotope ultra performance liquid chromatographic tandem mass spectrometric quantification of tissue content and activity of phenylethanolamine N-methyltransferase, the crucial enzyme responsible for synthesis of epinephrine

Here we describe a novel method utilizing double stable isotope ultra performance liquid chromatography-tandem mass spectrometry to measure tissue contents and activity of phenylethanolamine N-methyltransferase (PNMT), the enzyme responsible for synthesis of the stress hormone, epinephrine. The meth...

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Autors principals: Qin, Nan, Peitzsch, Mirko, Menschikowski, Mario, Siegert, Gabriele, Pacak, Karel, Eisenhofer, Graeme
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671350/
https://ncbi.nlm.nih.gov/pubmed/23224622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-012-6599-x
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