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Mathematical modeling of genome replication

Eukaryotic DNA replication is initiated from multiple sites on the chromosome, but little is known about the global and local regulation of replication. We present a mathematical model for the spatial dynamics of DNA replication, which offers insight into the kinetics of replication in different typ...

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Main Authors: Retkute, Renata, Nieduszynski, Conrad A., de Moura, Alessandro
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671344/
https://ncbi.nlm.nih.gov/pubmed/23030953
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