BRCA1 is a negative modulator of the PRC2 complex

The Polycomb-repressive complex 2 (PRC2) is important for maintenance of stem cell pluripotency and suppression of cell differentiation by promoting histone H3 lysine 27 trimethylation (H3K27me3) and transcriptional repression of differentiation genes. Here we show that the tumour-suppressor protein...

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Bibliografski detalji
Glavni autori: Wang, Lan, Zeng, Xianzhuo, Chen, Shuai, Ding, Liya, Zhong, Jian, Zhao, Jonathan C, Wang, Liguo, Sarver, Aaron, Koller, Antonius, Zhi, Jizu, Ma, Yupo, Yu, Jindan, Chen, Junjie, Huang, Haojie
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671259/
https://ncbi.nlm.nih.gov/pubmed/23624935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.95
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