טוען...
BRCA1 is a negative modulator of the PRC2 complex
The Polycomb-repressive complex 2 (PRC2) is important for maintenance of stem cell pluripotency and suppression of cell differentiation by promoting histone H3 lysine 27 trimethylation (H3K27me3) and transcriptional repression of differentiation genes. Here we show that the tumour-suppressor protein...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
European Molecular Biology Organization
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671259/ https://ncbi.nlm.nih.gov/pubmed/23624935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.95 |
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