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Mild Palladium-Catalyzed C–H Alkylation Using Potassium Alkyltrifluoroborates in Combination with MnF3

[Image: see text] A Pd-catalyzed method for ligand-directed C–H alkylation with organoboron reagents is described. The combination of potassium organotrifluoroborates, MnF(3), and a Pd(II) catalyst effects pyridine and amide-directed C–H alkylation. These reactions proceed under mild conditions (25–...

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Bibliografiske detaljer
Main Authors: Neufeldt, Sharon R., Seigerman, Cydney K., Sanford, Melanie S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670967/
https://ncbi.nlm.nih.gov/pubmed/23597105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol400888r
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