UV light-induced cyclobutane pyrimidine dimers are mutagenic in mammalian cells.

We used a simian virus 40-based shuttle vector plasmid, pZ189, to determine the role of pyrimidine cyclobutane dimers in UV light-induced mutagenesis in monkey cells. The vector DNA was UV irradiated and then introduced into monkey cells by transfection. After replication, vector DNA was recovered f...

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Autori principali: Protić-Sabljić, M, Tuteja, N, Munson, P J, Hauser, J, Kraemer, K H, Dixon, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC367080/
https://ncbi.nlm.nih.gov/pubmed/3540589
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