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Intrinsic Polymerase Activities of UmuD′(2)C and MucA′(2)B Are Responsible for Their Different Mutagenic Properties during Bypass of a T-T cis-syn Cyclobutane Dimer
In wild-type Escherichia coli, translesion replication is largely dependent upon the UmuD′(2)C complex (DNA polymerase V [polV]) or its plasmid-encoded homologs, such as MucA′(2)B. Interestingly, both the efficiency of translesion replication of a T-T cis-syn dimer and the spectra of mutations obser...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC111279/ https://ncbi.nlm.nih.gov/pubmed/10735873 |
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