Intrinsic Polymerase Activities of UmuD′(2)C and MucA′(2)B Are Responsible for Their Different Mutagenic Properties during Bypass of a T-T cis-syn Cyclobutane Dimer

In wild-type Escherichia coli, translesion replication is largely dependent upon the UmuD′(2)C complex (DNA polymerase V [polV]) or its plasmid-encoded homologs, such as MucA′(2)B. Interestingly, both the efficiency of translesion replication of a T-T cis-syn dimer and the spectra of mutations obser...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Principais autores:	O'Grady, Paul I., Borden, Angela, Vandewiele, Dominique, Ozgenc, Ali, Woodgate, Roger, Lawrence, Christopher W.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Assuntos:	Genetics and Molecular Biology
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111279/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10735873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.8.2285-2291.2000
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