Long noncoding RNA programs active chromatin domain to coordinate homeotic gene activation

The genome is extensively transcribed into long intergenic noncoding RNAs (lincRNAs), many of which are implicated in gene silencing(1,2). Potential roles of lincRNAs in gene activation are much less understood(3,4,5). Development and homeostasis require coordinate regulation of neighboring genes th...

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Hlavní autoři: Wang, Kevin C., Yang, Yul W., Liu, Bo, Sanyal, Amartya, Corces-Zimmerman, Ryan, Chen, Yong, Lajoie, Bryan R., Protacio, Angeline, Flynn, Ryan A., Gupta, Rajnish A., Wysocka, Joanna, Lei, Ming, Dekker, Job, Helms, Jill A., Chang, Howard Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670758/
https://ncbi.nlm.nih.gov/pubmed/21423168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09819
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