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The long-range interaction landscape of gene promoters

The vast non-coding portion of the human genome is awash in functional elements and disease-causing regulatory variants. The principles defining the relationships between these elements and distal target genes remain unknown. Promoters and distal elements can engage in looping interactions that have...

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Detalhes bibliográficos
Main Authors: Sanyal, Amartya, Lajoie, Bryan, Jain, Gaurav, Dekker, Job
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555147/
https://ncbi.nlm.nih.gov/pubmed/22955621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11279
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