The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

We developed a general approach that combines Chromosome Conformation Capture Carbon Copy with the Integrated Modeling Platform to generate high-resolution three-dimensional models of chromatin at the Mb scale. We applied this approach to the ENm008 domain on human chromosome 16 containing the α-glo...

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Detalhes bibliográficos
Main Authors: Baù, Davide, Sanyal, Amartya, Lajoie, Bryan R., Capriotti, Emidio, Byron, Meg, Lawrence, Jeanne B., Dekker, Job, Marti-Renom, Marc A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056208/
https://ncbi.nlm.nih.gov/pubmed/21131981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1936
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