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The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules
We developed a general approach that combines Chromosome Conformation Capture Carbon Copy with the Integrated Modeling Platform to generate high-resolution three-dimensional models of chromatin at the Mb scale. We applied this approach to the ENm008 domain on human chromosome 16 containing the α-glo...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056208/ https://ncbi.nlm.nih.gov/pubmed/21131981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1936 |
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