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Membrane-binding properties of the Factor VIII C2 domain
Factor VIII functions as a cofactor for Factor IXa in a membrane-bound enzyme complex. Membrane binding accelerates the activity of the Factor VIIIa–Factor IXa complex approx. 100000-fold, and the major phospholipid-binding motif of Factor VIII is thought to be on the C2 domain. In the present study...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670696/ https://ncbi.nlm.nih.gov/pubmed/21210768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101797 |
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