Recombination of homologous DNA fragments transfected into mammalian cells occurs predominantly by terminal pairing.

The mechanism by which double-strand cleavages stimulate the joining of plasmid DNA fragments introduced into cultured mammalian cells was investigated by cotransfecting pairs of plasmids encoding deletion mutations in a dominant selectable gene into LMtk- cells. Plasmid recombination substrates wer...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Anderson, R A, Eliason, S L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.9.3246-3252.1986
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