Recombination of homologous DNA fragments transfected into mammalian cells occurs predominantly by terminal pairing.
The mechanism by which double-strand cleavages stimulate the joining of plasmid DNA fragments introduced into cultured mammalian cells was investigated by cotransfecting pairs of plasmids encoding deletion mutations in a dominant selectable gene into LMtk- cells. Plasmid recombination substrates wer...
Shranjeno v:
| izdano v: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1986
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.9.3246-3252.1986 |
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