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Mapping the Epitopes of a Neutralizing Antibody Fragment Directed against the Lethal Factor of Bacillus anthracis and Cross-Reacting with the Homologous Edema Factor

The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal factor (LF), plays an essential role in anthrax pathogenesis. PA also interacts with the edema factor (EF, 20% identity with LF) to form the edema toxin (ET), which has a lesser role in anthrax pathog...

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Detalhes bibliográficos
Main Authors: Thullier, Philippe, Avril, Arnaud, Mathieu, Jacques, Behrens, Christian K., Pellequer, Jean-Luc, Pelat, Thibaut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669279/
https://ncbi.nlm.nih.gov/pubmed/23741517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065855
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