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Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity

BACKGROUND: Ricin is a lethal toxin that inhibits protein synthesis. It is easily extracted from a ubiquitously grown plant, Ricinus communis, and thus readily available for use as a bioweapon (BW). Anti-ricin antibodies provide the only known therapeutic against ricin intoxication. RESULTS: In this...

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Detalhes bibliográficos
Main Authors: Pelat, Thibaut, Hust, Michael, Hale, Martha, Lefranc, Marie-Paule, Dübel, Stefan, Thullier, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716335/
https://ncbi.nlm.nih.gov/pubmed/19563687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-60
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