1,25-Dihydroxyvitamin D(3) Inhibits Podocyte uPAR Expression and Reduces Proteinuria

BACKGROUND: Accumulating studies have demonstrated that 1,25-Dihydroxyvitamin D(3) (1,25(OH)2D3) reduces proteinuria and protects podocytes from injury. Recently, urokinase receptor (uPAR) and its soluble form have been shown to cause podocyte injury and focal segmental glomerulosclerosis (FSGS). He...

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Hoofdauteurs: Ma, Jianchao, Zhang, Bin, Liu, Shuangxin, Xie, Shaoting, Yang, Yun, Ma, Juan, Deng, Yujun, Wang, Wenjian, Xu, Lixia, Li, Ruizhao, Zhang, Li, Yu, Chunping, Shi, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669128/
https://ncbi.nlm.nih.gov/pubmed/23741418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064912
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