1,25-Dihydroxyvitamin D(3) Inhibits Podocyte uPAR Expression and Reduces Proteinuria

BACKGROUND: Accumulating studies have demonstrated that 1,25-Dihydroxyvitamin D(3) (1,25(OH)2D3) reduces proteinuria and protects podocytes from injury. Recently, urokinase receptor (uPAR) and its soluble form have been shown to cause podocyte injury and focal segmental glomerulosclerosis (FSGS). He...

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Main Authors: Ma, Jianchao, Zhang, Bin, Liu, Shuangxin, Xie, Shaoting, Yang, Yun, Ma, Juan, Deng, Yujun, Wang, Wenjian, Xu, Lixia, Li, Ruizhao, Zhang, Li, Yu, Chunping, Shi, Wei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669128/
https://ncbi.nlm.nih.gov/pubmed/23741418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064912
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