Specific peripheral B cell tolerance defects in patients with multiple sclerosis

Multiple sclerosis (MS) is a genetically mediated autoimmune disease of the central nervous system. B cells have recently emerged as major contributors to disease pathogenesis, but the mechanisms responsible for the loss of B cell tolerance in patients with MS are largely unknown. In healthy individ...

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Detalhes bibliográficos
Main Authors: Kinnunen, Tuure, Chamberlain, Nicolas, Morbach, Henner, Cantaert, Tineke, Lynch, Megan, Preston-Hurlburt, Paula, Herold, Kevan C., Hafler, David A., O’Connor, Kevin C., Meffre, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668812/
https://ncbi.nlm.nih.gov/pubmed/23676463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68775
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