mSWI/SNF (BAF) Complexes Facilitate Decatentation of DNA by Topoisomerase IIα

Recent exon sequencing studies of human tumors have revealed that subunits of mSWI/SNF or BAF complexes are mutated in more than 20% of all human malignancies,(1,2) yet the mechanisms involved in tumor suppression are unclear. BAF chromatin remodeling complexes are polymorphic assemblies that use en...

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Hlavní autoři: Dykhuizen, Emily C., Hargreaves, Diana C., Miller, Erik, Cui, Kairong, Korshunov, Andrey, Kool, Marcel, Pfister, Stefan, Cho, Yoon-Jae, Zhao, Keji, Crabtree, Gerald R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668793/
https://ncbi.nlm.nih.gov/pubmed/23698369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12146
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