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Ataxia Telangiectasia-mutated- and Rad3-related Protein Regulates the DNA Damage-induced G(2)/M Checkpoint through the Aurora A Cofactor Bora Protein
Polo-like kinase1 (Plk1) activation is inhibited in response to DNA damage, and this inhibition contributes to the activation of the G(2)/M checkpoint, although the molecular mechanism by which Plk1 is inhibited is not clear. Here we report that the DNA damage signaling pathway inhibits Plk1 activit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668769/ https://ncbi.nlm.nih.gov/pubmed/23592782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456780 |
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