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Plasmid Accumulation Reduces Life Span in Saccharomyces cerevisiae

Aging in the yeast Saccharomyces cerevisiae is under the control of multiple pathways. The production and accumulation of extrachromosomal rDNA circles (ERCs) is one pathway that has been proposed to bring about aging in yeast. To test this proposal, we have developed a plasmid-based model system to...

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Hlavní autoři: Falcón, Alaric A., Aris, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668691/
https://ncbi.nlm.nih.gov/pubmed/12904293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M307025200
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