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Plasmid Accumulation Reduces Life Span in Saccharomyces cerevisiae
Aging in the yeast Saccharomyces cerevisiae is under the control of multiple pathways. The production and accumulation of extrachromosomal rDNA circles (ERCs) is one pathway that has been proposed to bring about aging in yeast. To test this proposal, we have developed a plasmid-based model system to...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668691/ https://ncbi.nlm.nih.gov/pubmed/12904293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M307025200 |
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