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Modulation of Life-span by Histone Deacetylase Genes in Saccharomyces cerevisiae

The yeast Saccharomyces cerevisiae has a limited life-span, which is measured by the number of divisions that individual cells complete. Among the many changes that occur as yeasts age are alterations in chromatin-dependent transcriptional silencing. We have genetically manipulated histone deacetyla...

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Detalhes bibliográficos
Main Authors: Kim, Sangkyu, Benguria, Alberto, Lai, Chi-Yung, Jazwinski, S. Michal
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25567/
https://ncbi.nlm.nih.gov/pubmed/10512855
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