A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity

Histone modifications are now well-established mediators of transcriptional programs that distinguish cell states. However, the kinetics of histone modification and their role in mediating rapid, signal-responsive gene expression changes has been little studied on a genome-wide scale. Vascular endot...

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Hlavní autoři: Zhang, Bing, Day, Daniel S., Ho, Joshua W., Song, Lingyun, Cao, Jingjing, Christodoulou, Danos, Seidman, Jonathan G., Crawford, Gregory E., Park, Peter J., Pu, William T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668360/
https://ncbi.nlm.nih.gov/pubmed/23547170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.149674.112
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