Wordt geladen...
A Conformational Switch in Complexin is Required for Synaptotagmin to Trigger Synaptic Fusion
The crystal structure of Complexin bound to a pre-fusion SNAREpin mimetic shows that the accessory helix extends away from the SNAREpin in an “open” conformation, binding another SNAREpin, and inhibiting its assembly to clamp fusion. In contrast, the accessory helix in the post-fusion complex parall...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668341/ https://ncbi.nlm.nih.gov/pubmed/21785412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2103 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|