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LRRK2: an éminence grise of Wnt-mediated neurogenesis?

The importance of leucine-rich repeat kinase 2 (LRRK2) to mature neurons is well-established, since mutations in PARK8, the gene encoding LRRK2, are the most common known cause of Parkinson’s disease. Nonetheless, despite the LRRK2 knockout mouse having no overt neurodevelopmental defect, numerous l...

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Autori principali: Berwick, Daniel C., Harvey, Kirsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668263/
https://ncbi.nlm.nih.gov/pubmed/23754980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00082
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