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LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same

Since the discovery of leucine-rich repeat kinase 2 (LRRK2) as a protein that is likely central to the aetiology of Parkinson’s disease, a considerable amount of work has gone into uncovering its basic cellular function. This effort has led to the implication of LRRK2 in a bewildering range of cell...

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Pubblicato in:Mol Neurodegener
Autori principali: Berwick, Daniel C., Heaton, George R., Azeggagh, Sonia, Harvey, Kirsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925518/
https://ncbi.nlm.nih.gov/pubmed/31864390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0344-2
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