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Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity

AMP-activated protein kinase (AMPK) is a sensor of cellular energy status. It is a heterotrimer composed of a catalytic α and two regulatory subunits (β and γ). AMPK activity is regulated allosterically by AMP and by the phosphorylation of residue Thr-172 within the catalytic domain of the AMPKα sub...

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Detalles Bibliográficos
Autores principales: Rubio, Teresa, Vernia, Santiago, Sanz, Pascual
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667731/
https://ncbi.nlm.nih.gov/pubmed/23552691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-11-0806
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