AMP-activated Protein Kinase Phosphorylates R5/PTG, the Glycogen Targeting Subunit of the R5/PTG-Protein Phosphatase 1 Holoenzyme, and Accelerates Its Down-regulation by the Laforin-Malin Complex

R5/PTG is one of the glycogen targeting subunits of type 1 protein phosphatase, a master regulator of glycogen synthesis. R5/PTG recruits the phosphatase to the places where glycogen synthesis occurs, allowing the activation of glycogen synthase and the inactivation of glycogen phosphorylase, thus i...

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Main Authors: Vernia, Santiago, Solaz-Fuster, M. Carmen, Gimeno-Alcañiz, José Vicente, Rubio, Teresa, García-Haro, Luisa, Foretz, Marc, de Córdoba, Santiago Rodríguez, Sanz, Pascual
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659182/
https://ncbi.nlm.nih.gov/pubmed/19171932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808492200
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