β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

The AMP-activated protein kinase (AMPK) is an αβγ heterotrimer that acts as a master metabolic regulator to maintain cellular energy balance following increased energy demand and increases in the AMP/ATP ratio. This regulation provides dynamic control of energy metabolism, matching energy supply wit...

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Hlavní autoři: Oakhill, Jonathan S., Chen, Zhi-Ping, Scott, John W., Steel, Rohan, Castelli, Laura A., Ling, Naomi, Macaulay, S. Lance, Kemp, Bruce E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984171/
https://ncbi.nlm.nih.gov/pubmed/20974912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009705107
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