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β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation

β1 integrin has been shown to promote metastasis in a number of tumor models, including breast, ovarian, pancreatic, and skin cancer; however, the mechanism by which it does so is poorly understood. Invasive membrane protrusions called invadopodia are believed to facilitate extracellular matrix degr...

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Detalhes bibliográficos
Main Authors: Beaty, Brian T., Sharma, Ved P., Bravo-Cordero, Jose J., Simpson, Mark A., Eddy, Robert J., Koleske, Anthony J., Condeelis, John
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667720/
https://ncbi.nlm.nih.gov/pubmed/23552693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-12-0908
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