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An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion

Invasive carcinoma cells use specialized actin polymerization-driven protrusions called invadopodia to degrade and possibly invade through the extracellular matrix during metastasis. Phosphorylation of the invadopodium protein cortactin is a master switch that activates invadopodium maturation and f...

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Bibliografiska uppgifter
Huvudupphovsmän: Mader, Christopher C., Oser, Matthew, Magalhaes, Marco A. O., Bravo-Cordero, Jose Javier, Condeelis, John, Koleske, Anthony J., Gil-Henn, Hava
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057139/
https://ncbi.nlm.nih.gov/pubmed/21257711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1432
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