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GENETIC CONTROL OF THE B CELL RESPONSE TO LPS: OPPOSING EFFECTS IN PERITONEAL VERSUS SPLENIC B CELL POPULATIONS

Lipopolysaccharide (LPS) from gram-negative bacteria activates B cells, enabling them to proliferate and differentiate into plasma cells. This response is critically dependent on the expression of TLR4, but other genes, such as RP105 and MHC class II, have also been shown to contribute to B cell LPS...

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Autori principali: VALE, AM, HAYASHI, E, GRANATO, A, SCHROEDER, HW, BELLIO, M, NOBREGA, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667601/
https://ncbi.nlm.nih.gov/pubmed/19937016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-009-0404-9
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