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GENETIC CONTROL OF THE B CELL RESPONSE TO LPS: OPPOSING EFFECTS IN PERITONEAL VERSUS SPLENIC B CELL POPULATIONS

Lipopolysaccharide (LPS) from gram-negative bacteria activates B cells, enabling them to proliferate and differentiate into plasma cells. This response is critically dependent on the expression of TLR4, but other genes, such as RP105 and MHC class II, have also been shown to contribute to B cell LPS...

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Detalhes bibliográficos
Main Authors: VALE, AM, HAYASHI, E, GRANATO, A, SCHROEDER, HW, BELLIO, M, NOBREGA, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667601/
https://ncbi.nlm.nih.gov/pubmed/19937016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-009-0404-9
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