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Growing Pains in Academic Drug Discovery

In a recent Perspective, Jonathon Baell argues that compounds published as drug leads by academic laboratories commonly contain functionality that identifies them as nonspecific “pan assay interference” compounds (PAINS). Baell’s article raises broad questions about why best practices for hit and le...

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書誌詳細
第一著者: Whitty, Adrian
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667403/
https://ncbi.nlm.nih.gov/pubmed/21644825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.44
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